Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2026
  • Volume: 19
  • Issue: 2

Chemometric Analysis of Flavonoids Profile in Prosopis cineraria Leaves using High Performance Liquid Chromatography (HPTLC)

1Research Scholar, PhD, Sagar Institute of Research and Technology-Pharmacy, Sanjeev Agrawal Global Educational University, Bhopal, India

2Professor, Sagar Institute of Research and Technology-Pharmacy, Sanjeev Agrawal Global Educational University, Bhopal, India

Abstract

Prosopis cineraria is a medicinal plant known for its rich flavonoid content, which plays a vital role in its pharmacological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. This study aimed to analyze the flavonoid profile of P. cineraria leaves using High-Performance Thin-Layer Chromatography (HPTLC) combined with chemometric techniques. The methanolic leaf extracts were prepared and subjected to HPTLC for the separation and identification of flavonoid compounds. Chemometric analysis was employed to improve compound differentiation and quantification. The results provided valuable insights into the diverse flavonoid composition of P. cineraria, highlighting its potential for pharmaceutical and nutraceutical applications. This study contributes to the standardization and quality control of herbal formulations containing P. cineraria extracts.

Keywords

Prosopis cineraria, Flavonoids, HPTLC, Chemometric analysis, Medicinal plant, Phytochemistry