Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2026
  • Volume: 19
  • Issue: 3

Impact of Diagnostic X-Ray Exposure on Blood Vessel Integrity in Albino Rats: An Electron Microscopy Analysis

  • Author:
  • Sameh Fawzy Elsonbaty1,*, Mohammad Chand Jamali2,**, Wadah M.A Khogali1,***, Hend Hamed1,****, Mohamed Abdelfatah Abdelmounim Mohamed2,*****, Maxime Merheb3,******, Adham Elsonbaty4,*******, Rehab Mohd Jamali5,********
  • Total Page Count: 5
  • Page Number: 1230 to 1234

1Department of Health & Laboratory Sciences, College of Medical and Health Sciences, Liwa University, Abu Dhabi, United Arab Emirates

2Department of Health & Laboratory Sciences, College of Medical and Health Sciences, Liwa University, Al Ain, Abu Dhabi, United Arab Emirates

3College of Health Sciences, Dubai Medical University, Dubai, United Arab Emirates

4Faculty of Medicine, October 6 University, Egypt

5College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

*Corresponding Author E-mail: sameh.elsonbaty@lu.ac.ae

**E-mail: mjamali68@gmail.com

***E-mail: maxime.merheb@dmu.ae

****E-mail: wadah.khogali@lu.ac.ae

*****E-mail: hend.ahmad@lu.ac.ae

******E-mail: mohammed.abdelfatah@lu.ac.ae

*******E-mail: samsonbaty@gmail.com

********E-mail: rehab.jamali@gmail.com

Abstract

The growing reliance on diagnostic X-ray imaging has raised concerns regarding its potential effects on cellular and tissue health. This research explores the impact of diagnostic X-ray exposure on the structural integrity of blood vessels, with a special focus on the aortic wall in rats. We analyzed the aorta's ultrastructural changes using electron microscopy by comparing patients exposed to X-rays to a control group. The findings revealed significant alterations in the aortic wall, including changes in the smooth muscle cells, elastic fibres, basal lamina, collagen deposition, and intracellular structures. These findings suggest that diagnostic X-ray exposure may disrupt the structural components of the aorta, potentially contributing to long-term vascular damage.

Keywords

X-ray, Blood Vessel Integrity, Microscopic Analysis, Smooth Muscle Cells, Elastic Fibres