Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2026
  • Volume: 19
  • Issue: 3

A Review Article on Hydrophilic Matrix Innovation

  • Author:
  • Jayanti Tiwari1,*, Sandeep Kumar Gupta1, Pooja Lodhi1, Sparsh Kumar Gupta1, Prem Gupta1, Poorvi Sahu1, Shivangi Gupta1
  • Total Page Count: 6
  • Page Number: 1415 to 1420

1Gyan Ganga Institute of Technology and Sciences, Jabalpur, India, 482003

*Corresponding Author E-mail: jtiwaripharma@yahoo.com

Abstract

Hydrogels are three-dimensional polymeric networks capable of absorbing and retaining substantial amounts of water while maintaining their structural integrity. Their unique properties such as high water content, tunable mechanical strength, flexibility, and excellent biocompatibility make them highly versatile for biomedical applications. Hydrogels can be synthesized from either natural or synthetic polymers, with their characteristics adjustable through variation in polymer composition, cross-linking density, and responsiveness to environmental stimuli. These materials are widely employed in tissue engineering, drug delivery systems, wound care, and biosensors. In drug delivery, hydrogels enables controlled, localized release of therapeutic agents, improving efficacy and reducing side effects. Their porous structure and moisture retention create an optimal environment for wound healing. In tissue engineering, they mimic the extracellular matrix, supporting cell adhesion, growth, and differentiation. Additionally, hydrogels can function as smart materials in biosensing due to their sensitivity to pH, temperature, and ionic strength. Despite their promise, challenges such as large-scale production and long-term stability remain. Ongoing research focuses on enhancing the biodegradability, mechanical properties, and functionality of hydrogels, positioning them as transformative materials in both medical and industrial fields.

Keywords

Hydrogel, Merits, Biocompatibility, Strength, Wound care, Diffusion