1Department of Pharmaceutical Analysis, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode,Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
10B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
11B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
2Department of Pharmaceutics, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi,Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
3B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
4B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
5B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
6B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
7B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
8B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
9B. Pharm Final Year, Shree Venkateshwara College of Paramedical Sciences, Othakuthirai, Gobi, Erode, Tamil Nadu, India. Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Chennai, India.
*Corresponding Author E-mail: princebieber28@gmail.com
Quercetin, a flavonoid widely present in fruits, vegetables, and medicinal plants, exhibits potent antioxidant, anti-inflammatory, antimicrobial, and cardiovascular protective effects. This study aimed to develop and validate a simple, rapid, sensitive, and cost-effective UV-visible spectrophotometric method for the quantification of quercetin in marketed Amla tablets. Standard and sample solutions were prepared and scanned at 256 nm, which was identified as the λmax. The method was validated according to ICH Q2(R1) guidelines for specificity, linearity (2-10 µg/mL, R2 = 0.9993), accuracy (99.81-100.7% recovery), precision (%RSD <2%), LOD (0.206 µg/mL), and LOQ (0.624 µg/mL). The proposed method showed no interfer ence from excipients, demonstrated robustness, and was successfully applied to commercially available Amla tablets. The method can be used for routine quality control and estimation of quercetin in pharmaceutical formulations.
Quercetin, UV-Visible Spectrophotometry, Amla Tablets, ICH Validation, Accuracy
