1Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Bd Med VI - BP 717Oujda60000Morocco.
2Higher Institute of Nursing Professions and Health Techniques, Al Maghreb Al Arabi Street, Al Farabi Hospital, Oujda, Morocco.
3Level 1 Urban Health CenterEl AouniaOujda, Morocco.
***Corresponding Author E-mail: nhbouanani@yahoo.fr
To respond to the health emergency caused by the Covid-19pandemic, several anti-Covid-19vaccines have been marketed. The speed of their development has prompted several questions about their safety. Therefore, the objective of this study is to carry out a systematic review of the side effects of the anti-Covid 19 vaccines, as well as their associated factors.
The recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were used for the selection of the studies included in this review. Articles published in English and French, aiming to identify “the side effects of anti-Covid-19 vaccines in adults” were included.
Most of the side effects associated with anti-Covid-19 vaccines are pain at the injection site, fatigue, myalgia and headache. Some rare side effects (myocarditis, thrombocytopenia) are more prevalent with specific types of vaccine (mRNA vaccine and adenoviral vaccine). Other serious adverse events (pulmonary embolism, pericarditis) have been reported but are rare. Conclusion: Anti-Covid 19 vaccines are reasonably safe. Further multicentre studies are needed to identify rare and long-term side effects in order to prevent or better manage them.
Anti Covid-19 Vaccines, Side Effects, Safety, Meta-analyses
