1Assistant Professor, Dept of pharmaceutics, CMR College of Pharmacy, Hyderabad, Telangana, India.
2Dept of pharmaceutics, CMR College of Pharmacy, Hyderabad, Telangana, India.
3Professor and Principal, CMR College of Pharmacy, Hyderabad, Telangana, India.
*Corresponding Author E-mail: iswariyapharma@gmail.com
By building intricate structures with phospholipids, phytosomes are a sort of drug delivery mechanism that increases the bioavailability of phytoconstituents, such as plant extracts or bioactive chemicals. The purpose of these complexes is to increase the medicinal efficiency of weakly water-soluble phytoconstituents by improving their solubility and absorption. The Greek terms “Phyto,” which means plant, and “soma,” which means body, are the source of the phrase “Phyto some." Phytosome technology is the method by which plant extracts or phytoconstituents are conjugated with phospholipids to form phytosomes. The inclusion of phospholipids, which are naturally occurring chemicals that play a significant role in cell membranes, in phytosomes helps to replicate the body's normal lipid composition, which improves the integration and absorption of the phytoconstituents. Because of their potential advantages, which include enhanced bioavailability, stability, and targeted administration of bioactive substances, phytosomes have found widespread application in the pharmaceutical, nutraceutical, and cosmeceutical industries. Because of the improved absorption through cell membranes made possible by the phospholipid complexation, phytosomes are a useful tactic for getting around the restrictions brought on by the low water solubility of many plant extracts. According to research, phytosomes can improve the medicinal properties of a variety of plant extracts, which can help create new formulations for the treatment of different medical diseases. To sum up, phytosomes offer a novel way to improve the effectiveness and bioavailability of substances derived from plants, opening up a promising new direction for the creation of sophisticated medication delivery systems and herbal formulations.
Phytosomes, Bioavailability, Stability and Solubility