A review of pluronic lecithin organogel (PLO) as a topical and transdermal drug delivery system

The purpose of this review is to give an insight into the considerable potentials of Pluronic Lecithin Organogel (PLO) as a topical and transdermal drug delivery system. PLO gel is a currently of interest to the compounding pharmacists because of it's versatile nature. Several therapeutic agents have been formulated as PLOs for their transport through topical route (for dermal or transdermal effect), with some very encouraging results. This review describes the recent reports of PLO formulation, evaluation, applications and other related aspects.