K.M.College of Pharmacy, Madurai -625107, Tamilnadu, India
*Corresponding Author E-mail: meeraharsa@yahoo.com
Bioassay guided fractionation of the Acetone, Benzene and Usnic acid (column ether extract) of Rimelia reticulata using drugs sensitive strain of Mycobacterium tuberculosis in vitro resulted in the Anti-TB activity. In enzyme activity the particular enzymes used are Amylase, Urease, Trypsin and Papain with standard inhibitors. For Amylase and Urease the Usnic acid and crude ether extracts shown 100% inhibition. For Trypsin and Papain alcohol extract shown 100% inhibition, in this study. The standard inhibitor for Amylase, Trypsin and Papain is Mercuric chloride. For Urease is P-chloro mercuric benzoate. Preliminary phytochemical screening was performed and different phytochemical constituents present in the extracts were identified.
Rimelia reticulata, Mycobacterium tuberculosis, Enzymes, Various extracts