Anti-inflammatory Action of Abutilon indicum (L.) Sweet Leaves by HRBC Membrane Stabilization

The ethanolic, chloroform and aqueous extracts of the leaves of Abutilon indicum (L.) Sweet (Malvaceae) known in Hindi as Atibala,were screened for anti-inflammatory activity.The dried powdered drug was successively extracted with several solvents and out of these the ethanolic,chloroform and aqueous extracts was selected for present study due to presence of several phytochemical in them.The prevention of hypotonicity induced HRBC membrane lysis was taken a measure of anti-inflammatory activity.All Three fraction showed a biphasic effect on the membrane stabilization.Their activities are comparable to that of standard drug diclofenac sodium.However their activities decreased with time.