Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2009
  • Volume: 2
  • Issue: 3

Formulation and evaluation of Isoniazide Dispersible tablets using Natural substances as Disintegrants

  • Author:
  • BS Kuchekar, SR Pattan, RK Godge, RB Laware, NS Dighe, SK Parjane, AN Merekar
  • Total Page Count: 4
  • Page Number: 585 to 588

Dept. of Pharmaceutics. Pravara Rural College of Pharmacy, Pravaranagar

*Corresponding Author E-mail: anmerekar@yahoo.co.in

Online published on 8 April, 2013.

Abstract

Dispersible tablets of Isoniazide were prepared using natural substances as disintegrant such as Ispaghula husk powder, Cassia tora powder, Cassia tora powder (defatted), Cassia nodosa powder in different concentration by direct compression method. Formulations were evaluated for the standard of dispersible tablets and were compared with marketed products. It was observed that all the formulations were acceptable with reasonable limits of standard required for dispersible tablets. The study reveals that natural gums used as disintegrants were effective in low concentration.

Keywords

Dispersible tablet, direct compression, Isoniazid, natural disintegrants