Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2009
  • Volume: 2
  • Issue: 4

Synthesis and Biological Evaluation of Chloroacetyl Derivatives of Some Schiff's Bases

  • Author:
  • P Muthumani, R Meera, Pratesh , N Chidambaranathan, P Devi, B Kameswari
  • Total Page Count: 6
  • Page Number: 824 to 829

K.M. College of Pharmacy, Uthangudi, Madurai – 625 107. TamilNadu, India

*Corresponding Author E-mail: sabareesanmuthu@gmail.com

Online published on 8 April, 2013.

Abstract

Synthesis of substituted 2-Azetidinone derivatives with chloro acetyl chloride along with their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and1HNMR spectroscopy. The antimicrobial activity of the synthesized compounds was evaluated, on Staphylococcus aureus, Pseudomonas aeruginosa. The anticonvulsant activity and anti inflammatory activities were also evaluated. The present investigation deals with the synthesized compounds possessing good anticonvulsant and anti inflammatory activity, moderate antibacterial activity.

Keywords

Chloro acetyl derivative, 2-Azetidionone, Antimicrobial activity, Anti convulsant activity, Anti inflammatory activity