1Dept. of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102. Karnataka
2Dept. of Pharmacology, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102. Karnataka
*Corresponding Author E-mail: babithamurthy@gmail.com
Online published on 8 April, 2013.
Some new pyrimidine derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with guanidine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.
Synthesis, Pyrimidines, Anti-inflammatory activity
