A Simple and Precise Method for the Estimation of Simvastatin in Formulations by UV-Visible Spectrophotometer

D Hepcy Kalarani; P Venkatesh; K Ravindra Reddy; A Dinakar

Year: 2009
Volume: 2
Issue: 4

A Simple and Precise Method for the Estimation of Simvastatin in Formulations by UV-Visible Spectrophotometer

Author:
D Hepcy Kalarani^1,, P Venkatesh¹, K Ravindra Reddy¹, A Dinakar²
Total Page Count: 2
Page Number: 882 to 883

¹P. Rami Reddy Memorial College of Pharmacy-Kadapa-516 003. Andhra Pradesh, India

²Vagdevi College of Pharmacy and Research Centre-Nellore-524 004. Andhra Pradesh, India

*Corresponding Author E-mail: hepcykr@rediffmail.com

Online published on 8 April, 2013.

Abstract

A simple and precise spectrophotometric method in ultra violet region has been developed for the estimation of simvastatin in its pharmaceutical dosage forms. Simvastatin exhibited maximum absorbance at 237.8nm in ethanol. It obeys Beer's law in the concentration range of 1-40mcg/ml. Results of the analysis were validated statistically and by recovery studies, repeatability studies.

Keywords

Simvastatin, UV, λ_max

A Simple and Precise Method for the Estimation of Simvastatin in Formulations by UV-Visible Spectrophotometer

Abstract

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