Pulsatile Drug Delivery Systems: Novel Approach on Control Drug Delivery

Pulsatile drug delivery system is a novel strategy developed to improve the efficiency of controlled drug delivery system in the treatment of the disease dependant on circadian rhythm such as asthma, arthritis, duodenal ulcer, cardiovascular diseases. It release drug in a pulsatile or staggered profile. Pulsatile drug delivery systems (PDDS) are gaining importance as these systems deliver the drug at specific time as per the pathophysiological need of the disease, resulting in improved patient therapeutic efficacy and compliance. This review focus on various methods that have been used for pulsatile release of drug. These systems have the potential to improve the quality of life for patients undergoing therapy with a variable dosing regime.