Novel Visible Spectrophotometric Methods for Estimation of Fenoverine in Pharmaceutical Formulations

Fenoverine is an antispasmodic drug. Two simple, sensitive and accurate spectrophotometric methods have been developed for the determination of fenoverine in pure state and in its pharmaceutical formulations. The developed Method A is based on the formation of picrate salt between picric acid and free base of fenoverine and it shows maximum absorption at λ_max 410 nm and Linearity in the range of 10–50 μg/mL. Method B involves reaction between free base of fenoverine and chloranilic acid. The developed chromogen in Method B shows maximum absorption at λ_max 525 nm and Linearity in the range of 100–500 μg/mL. The results obtained were statistically evaluated and were found to be accurate and reproducible.