Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2010
  • Volume: 3
  • Issue: 2

Evaluation of Anticonvulsant Activity of Novel Substituted 2-Mercaptobenzimidazole Derivatives

  • Author:
  • Ravi N Tiwari1,, KG Bothara1, Gurmeet Singh Chhabra1, Sarang Kulkarni2
  • Total Page Count: 2
  • Page Number: 466 to 467

1Department of Pharmaceutical Chemistry, NMIMS University, Shirpur Campus Dist. Dhule (M.S) India

2Siddhant College of Pharmacy Sudumbare, Pune (M.S.) India

*Corresponding Author E-mail: ravisun4@rediffmail.com

Online published on 3 April, 2013.

Abstract

Mannich bases of sulphonamide substituted 2-mercaptobenzimidazole compounds were synthesized from 2-mercaptobenzimidazole by reacting with aldehyde like formaldehyde and the various sulphonamides. Synthesized compounds were characterized by spectral studies and evaluated for antibacterial activities. The statistical analysis was done by students“ t ”test and the values were expressed as Mean ± SEM.

Keywords

Mannich Bases Sulphonamide Substituted 2-Mercaptobenzimidazole, Anti-Convulsant Activity