1Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM University, Kattankulathur– 603 203, Kancheepuram District, (T.N.)
2Department of Pharmaceutical Chemistry, K.M.College of Pharmacy, Uthangudi, Madurai – 625 107 (T.N.)
*Corresponding Author E-mail: xavilatha@yahoo.co.in
Online published on 3 April, 2013.
The effect of methanolic extract of aerial parts of Tephrosia spinosa was investigated in rats to evaluate antiulcer activity by using Indomethacin induced plus pyloric ligation ulcer model. The parameters taken for antiulcer activity were the total gastric volume secretion, ulcer score, total acidity, pH and the ulcer index. The methanolic extract of aerial parts of Tephrosia spinosa showed significantly (P < 0.001) decreased when compared with the control treated group total gastric volume (6.12 ± 0.09) ml, ulcer score (3.17 ± 0.123) total acidity (70.32 ± 2.91) m eq/L/100g.
Tephrosia spinosa, Papilionaceae, Methanolic extract, Antiulcer activity
