Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2010
  • Volume: 3
  • Issue: 3

Validated Spectrophotometric Determination of Prulifloxacin in Pharmaceutical Formulation

  • Author:
  • A.G. Sambhare, D.R. Chaple, S.M. Dhole, M.H. Ghante
  • Total Page Count: 3
  • Page Number: 733 to 735

J. L. Chaturvedi College of Pharmacy, Electronic Zone Building, MIDC Hingna Road, Nagpur-440016, India, Phone- 07104-232169, 9860667108

*Corresponding Author E-mail: amit_sambhare@rediffmail.com

Online published on 3 April, 2013.

Abstract

A simple, sensitive, accurate and precise spectrophotometric method has been developed for the estimation of prulifloxacin in pharmaceutical formulation. Prulifloxacin shows maximum absorbance at 273 nm in 0.1 N HCl. The linearity was observed in the concentration range of 2–14 μg/mL. The method was validated statistically. The developed methods have been successfully applied for the determination of prulifloxacin in tablet dosage form. The recovery studies confirmed the accuracy of the proposed method.

Keywords

Prulifloxacin, spectrophotometry