1Department of Pharmaceutical Sciences, Saurashtra University, Rajkot-360005, Gujarat, India
2Department of Quality Assurance, Maliba pharmacy College, Bardoli, Gujarat, India
3Department of Quality Assurance, L.M. College of Pharmacy, Ahmedabad-380009, Gujarat, India
4Veerayatan Institute of Pharmacy, Mandvi-370460, Gujarat, India
*Corresponding Author E-mail: nkpatel99@gmail.com
Online published on 3 April, 2013.
Aceclofenac is [[[2-[(2, 6-dichlorophenyl) amino] phenyl] acetyl] oxy] acetic acid. Photodegradation product of aceclofenac in methanol was synthesized in laboratory. Photodegradation product characterized and identified by Mass spectrum, Infrared spectrum and HPTLC study. Photodegradation of Aceclofenac in methanol gives Methyl-[[[2-[(2,6-dichlorophenyl) amino] phenyl] acetyl] oxy] acetate (Methyl ester of Aceclofenac) which is also reported in British pharmacopoeia as one of the impurities.
Aceclofenac, Photodegradation, Photoproduct
