Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2010
  • Volume: 3
  • Issue: 3

Hepato-Protective Activity of the Water Extract of Launaea intybacea (Jacq) Beauv in Paracetomol Induced Hepato-Toxicity in Albino Rats

  • Author:
  • S.B. Takate1,, R.D. Pokharkar1, V.V. Chopade2, V.N. Gite1
  • Total Page Count: 3
  • Page Number: 815 to 817

1Agasti Arts, Comers and Dadasaheb Rupwate Science College, Akole, Dist-Ahmednagar, 422601 (MH) India

2Modern College of Pharmacy Nigdi, Pune-411 044

*Corresponding Author E-mail: sbtakate@rediffmail.com

Online published on 3 April, 2013.

Abstract

The present study was conducted to evaluate the hepato-protective activity of water extract of aerial parts of Launaea intybacea are evaluated in paracetamol-induced hepatotoxicity in albino rats. Silymarin (200mg/kg) was given as reference standard. The water extract of aerial parts of Launaea intybacea have shown very significant hepatoprotection against paracetamol-induced hepatotoxicity in albino rats in reducing serum total bilirubin, SALP, SGPT, SGOT levels and liver homogenates LPO, SOD, CAT, GPX, GST and GSH levels.

Keywords

Launaea intybacea, hepatotoxicity, paracetomol and silymarin