Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2010
  • Volume: 3
  • Issue: 4

Preclinical Evaluation of Antidiabetic Effect of Pedilanthus tithymaloides Extracts in Streptozotocin (STZ) Induced Diabetic Rats

  • Author:
  • S. Adhikary1,, C.C. Kandar1, P.K. Haldar2, A. Basu1, S. Choudhury1
  • Total Page Count: 2
  • Page Number: 1132 to 1133

1Department of Pharmaceutical Chemistry, Institute of Pharmacy, Jalpaiguri; West Bengal; India – 735 101

2Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University, Kolkata – 700 032

*Corresponding Author E-mail: sadhikari101@rediffmail.com

Online published on 3 April, 2013.

Abstract

Dried and powdered leaves of the plant Pedilanthus tithymaloides was extracted successively with chloroform and methanol using shoxlet extractor and the extracts were dried under reduced pressure at a temperature not exceeding 40°C. These extracts were subjected to different phytochemical tests and in the evaluation of antidiabetic potential on streptozotocin induced diabetic rats. Both the extract showed significant antidiabetic activity.

Keywords

Antidiabetic activity, streptozotocin induced diabetes, Pedilanthus tithymaloides