Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 1

Comparative Study on Hypoglycemic, Hypolipidemic Effects of Terminalia arjuna and Murraya koenigii in Alloxan-Induced Diabetic Albino Rats

  • Author:
  • T.M.M. John Bastin1, Panagal Mani2, R. Arun kumar3,, Muthuvel Arumugam4
  • Total Page Count: 3
  • Page Number: 57 to 59

1PG and Research Lab, Department of Biotechnology, Tamilvel Umamaheswaranar Karanthai Arts College, Thanjavur-613002, Tamil Nadu, India

2Dept. of Zoology and Biotechnology, A.V.V.M Sri Pushpam College, Poondi, Thanjavur-613 503, Tamil Nadu

3PG and Research Lab, Dept. of Biotechnology, Marudhu Pandiyar College, Thanjavur-613 403, Tamil Nadu

4Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai – 608 502, Tamilnadu

*Corresponding Author E-mail: arunkumarkarthi@yahoo.com

Online published on 3 April, 2013.

Abstract

The aim of the present study was designed to compare the possible therapeutic effects of Terminalia arjuna and Murraya koenigii methanolic extracts against diabetes. Serum glucose level, lipid profile and pancreas histology were estimated after administration of the extracts. Applied doses did not cause any acute toxicity or behavioral changes. In conclusion, T. arjuna produced a significant hypoglycemic effect while M. koenigii prove to have a hypolipidemic activity at dose level of 200 mg/kg.

Keywords

T. arjuna, M. koenigii, β-cells, serum lipids