Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 1

Laxative and Anthelmintic Potential of Cassia alata Flower Extract

  • Author:
  • R.S. Adnaik, D.A. Bhagwat, I.D. Raut, S.K. Mohite, C.S. Magdum
  • Total Page Count: 3
  • Page Number: 98 to 100

Department of Pharmacology, Rajarambapu College of Pharmacy, Kasegaon, Tal. Walwa, Dist. Sangli 415 404, Maharashtra, India

Online published on 3 April, 2013.

Abstract

The present study was undertaken to screen the laxative and anthelmintic activity of Cassia alata flowers. The laxative activity was performed at a dose of 100 mg/kg and 200 mg/kg according to Cappaso et al in albino rats. Anthelmintic activity was evaluated separately on adult Indian earthworms, Pheritima posthuma by the method of Nargund. Agaragar and piperazine citrate were used a standard drugs for laxative and anthelmintic activity respectively. The flower extract was found to produce significant (p>0.05) and dose-dependent increase in fecal output showing laxative activity; the 200 mg/kg dose being more potent. The extract was also found to paralyze and cause death of worms; showing significant anthelmintic activity.

Keywords

Laxative, Pheretima posthuma, Cassia alata Linn, agar-agar