Isolation of Active Constituent of Acorus calamus Rhizomes Extract and Evaluation of its Anti-cancer Activity

In present work, attempt was made to study anti-cancer activity of Acorus calamus rhizomes. From the results it is clearly proved that rhizomes of Acorus calamus showed promising anti-cancer activity. Preliminary phytochemical screening revealed that alkaloid might be responsible for anti-cancer activity. Isolated compound gave positive test for alkaloid. The anti-cancer activity of methanolic extract and isolated compound was carried out by Onion cell and Yeast cell models. The results showed anti-cancer activity when compared to methotrexate, which was used as standard.