Faculty of Pharmacy, Sri Ramachandra University, Porur, Chennai, India – 600116
*Corresponding author: sheela_phyto@rediffmail.com
Rheumatoid arthritis is a major ailment among rheumatic disorders. It is a chronic condition with multiple causation and affects the people in their most active period of their life. Traditional ethno medical uses indicate the selected medicinal plant Grewia tiliaefolia (Aerial parts) is used to treat wound, ulcer and skin disease1. Literature reveals that pharmacognistical evaluation has reported for the presence of glycosides, proteins, saponins, carbohydrate, tannins etc2. Since no further scientific study has been made in vitro anti arthritic activity so an attempt has been made to carry out the present research work. The present study deals with the in-vitro anti arthritic activity using effect of membrane stabilization and protein denaturation using different concentrations. The results are compared with standard drug. The methanolic extract of the selected medicinal plant showed significant activity.
Grewia tiliafolia, anti arthritic, membrane stabilization, protein denaturation