Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 3

Microwave Assisted Synthesis of Fluoro-Pyrazole Derivatives for Antiinflammatory Activity.

  • Author:
  • Sahu Sudeep1, Dey Tathagata2,, Khaidem Somila2, Y. Jyothi2
  • Total Page Count: 7
  • Page Number: 413 to 419

1SAF Fermion Ltd, Millennium City, Information Technology Park, Kolkata-700 091

2East Point College of Pharmacy, Bidarahalli, Virgonagar Post, Bangalore – 560 049

*Corresponding Author E-mail: tathagatad@gmail.com

Online published on 3 April, 2013.

Abstract

A series of fluoro-pyrazole derivatives have been synthesized and evaluated for anti-inflammatory screening using formali induce rat paw edema model. The studies of synthesized compounds were characterized by TLC, IR, 1H NMR analysis. These compounds have shown promising anti-inflammatory activity when compared with the standard drug diclofenac sodium.

Keywords

Fluoro-pyrazole, Chalcone, Anti-inflammatory activity