Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 3

Compatibility Study of Aceclofenac and Tablet Disintegrants by Thermal and Nonthermal Methods

  • Author:
  • Monica R.P. Rao2, Devidas G. Bachhav1,, Ramdas B. Rode3, Komal R. Nikam1, Namrata D. Pathade1
  • Total Page Count: 5
  • Page Number: 423 to 427

1MGV's S.P.H.College of Pharmacy, Malegaon, Dist: Nashik, Maharashtra

2AISSSMS College of Pharmacy, Pune, Maharashtra

3R.G. Sapkal College of Pharmacy, Nashik, Maharashtra

*Corresponding Author E-mail: devidas015@yahoo.co.in

Online published on 3 April, 2013.

Abstract

Drug excipients compatibility study is important preformulation tool for the selection of excipients prior to large scale development trials, thereby helpful to avoid potential stability problems. The present investigation was aimed at Compatibility study of Aceclofenac, an NSAID with some tablet disintegrants as Starch 1500, Croscarmellose Sodium and Sodium starch glycolate, by thermal method (Differential Scanning Calorimetry) and results of DSC were confirmed by nonthermal methods (IR and Assay).

Keywords

Compatibility study, DSC, IR, Excipients, Thermal, Nonthermal