Considerable research efforts have been directed towards developing safe and efficient chitosan-based particulate drug delivery systems. The present review outlines the ionotropic gelation method for the preparation of chitosan-based nanoparticulate drug delivery systems published over the past decade. From a literature survey, it is realized that research activities on chitosan micro/nanoparticulate systems containing various drugs for different therapeutic applications have increased at the rapid rate. Hence ionotropic gelation method can use to prepare these chitosan nanoarticles as it is very simple and having lots of advantages then other methods.
Chitosan, Nanoparticles, Ionotropic gelation
