Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 4

Two Wavelength Method for Estimation of Indapamide and Perindopril Erbumine in Combined Tablet Dosage Form

  • Author:
  • S.S. Kale, R.L. Bakal, A.V. Chandewar, R.S. Sakhare
  • Total Page Count: 4
  • DOI:
  • Page Number: 545 to 548

Department of Quality Assurance, P. Wadhwani College of Pharmacy, Yavatmal-445 001 (M.S.)

Abstract

A new, simple, accurate and sensitive UV-spectrophotometric two wavelength method has been developed for simultaneous determination of Indapamide and Perindopril Erbumine in combined pharmaceutical dosage form. Two wavelength i, e 220 nm and 240 nm were selected for estimation of Indapamide where as wavelength 216 nm was selected for estimation of Perindopril Erbumine using Methanol as solvent. Indapamide and Perindopril Erbumine shows linearity in the concentration range of 2–20 μg/ml and 4–40 μg/ml respectively. The method was validated statistically.

Keywords

Indapamide, Perindopril Erbumine Two wavelength method