Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 4

Development and Validation of Spectrophotometric Method for Mesalamine in Pure and In Tablets

  • Author:
  • Lalit Jejurkar, K.K. Tapar, M.D. Game, Tushar Birari, Gokul Ghenge
  • Total Page Count: 3
  • Page Number: 589 to 591

Vidyabharti College of Pharmacy, Department of P.G. and Research, Amravati-444602

*Corresponding Author E-mail: lalitjejurkar@gmail.com

Online published on 3 April, 2013.

Abstract

A simple UV spectrophotometric method for the analysis of Mesalamine was developed to analyze the drug in bulk and in tablet formulation. In this method the simple UV spectrum of mesalamine in phosphate buffer pH 6.8 was obtained which exhibits absorption maxima (λ max) at 331.0 nm. The Beers law ranges was followed in the concentration range of 5–100 μg/ml. The proposed method does not require any separation of soluble excipients as they do not influence at the selected wavelength and assay conditions.

Keywords

Mesalamine, Spectrophotometric Method, Phosphate buffer pH-6.8