Synthesis and Biological Activities of Some Novel Heterocyclic Compounds Containing Thiazolidinone Derivatives

Amino group of thiazole moiety have been treated with various aromatic aldehydes gave corresponding Schiff's bases, 3A-G. These Schiff's bases have been reacted with thioglycolic acid, anhydrous zinc chloride and N,N�-dimethyl Formamide as a solvent to get corresponding novel thiazolidinone derivatives, 4A-G. Structures of all the newly synthesized compounds were confirmed by IR, ¹H NMR, and mass spectral data. The synthesized compounds were evaluated for their antioxidant activity. Few compounds were found with potent antioxidant activity.