Research Journal of Pharmacy and Technology

Urinary tract infections (UTI's) are the most common bacterial infection. Escherichia Coli is the primary urinary tract pathogen. When large number of antibiotics are available it will enhances the inappropriate antibiotic choice. DU90% is an inexpensive, flexible and simple method for assessing the quality of drugs prescribing in routine health care. This research aims to find out DU90% of UTIs drug and promote rational use of antibiotics used in UTIs.

Study was conducted in 100 patients of UTI's after Ethics Committee approval and patients written informed consent was taken before enrolling them. Data of antibiotic prescription were obtained from patient's medical record. Quantity of antibiotics utilization was calculated as number of DDD/1000/DAY based on ATC/DDD system release by WHO collaborating centre for drug statistics methodology.Antibiotics were ranked by percentage of DDD/1000/DAY and antibiotics that accounted for 90% (DU90%) were determined. Prescribing and patient care indicators were calculated.

Five antibiotics found within DU90% segment -Norfloxacin, Cefixime, Amoxicillin, Metronidazole and Ciprofloxacin Prescribing indicators-% of drug prescribed from essential drug list-62.5 and Average no. of drugs per encounter -1.54, Patient care indicators-Average consultation time -5.06 min. and Average dispensing time -4.42 min., % of drug actually dispensed -67.

This study gives drugs most commonly used in tertiary care hospital of Nasik for UTIs treatment, within which 62.5% were from essential drug list and Norfloxacin found most commonly used drug. This study results will help practitioners of tertiary care hospital to assessing the overall quality in prescribing.