Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2011
  • Volume: 4
  • Issue: 9

Antiulcer Activity of Leaf Extract of Lawsonia inermis in Albino rats

  • Author:
  • Venkateshwarlu Goli1,, Sravan Prasad Macharla2, K. Vijaya Bhasker1, N.L Gowrishankar3, J. Bhaskar1, Ch. Dhanalakshmi4
  • Total Page Count: 3
  • Page Number: 1436 to 1438

1Department of Pharmacognosy, Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Andhra Pradesh, India 508001

2GBN Institute of Pharmacy, Ghatkesar, RR District, Andhra Pradesh, India

3Department of Pharmacognosy, Swami Viveka Nanda Institute of Pharmaceutical Sciences, Bhuvanagiri, Nalgonda, Andhra Pradesh, India508001

4Holy Mary Institute of Technology and Sciences, RR District, Andhra Pradesh, India

*Corresponding Author E-mail: venkatvenki505@yahoo.in

Abstract

The present work was evaluated anti-ulcer potential of the ethanol extract of leaf of Lawsonia inermis against in vivo indomethacin-induced gastric ulcer using pylorus ligation method. All the dose of the leaf extract (100, 200 and 400 mg/kg) significantly (P□0.01) reduced the ulcer index in this experiment. In conclusion, the present study provides preliminary data on the antiulcer potential of Trianthema portulacastrum leaf and support the traditional uses of the plant for the treatment of gastric ulcer.

Keywords

Lawsonia inermis leaf, ethanol extract, gastric ulcer, pylorus ligation, indomethacin, induced gastric ulcers, ulcer index