1Department of Pharmacognosy, Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Andhra Pradesh, India – 508001
2GBN Institute of Pharmacy, Ghatkesar, RR District, Andhra Pradesh, India
3Department of Pharmacognosy, Swami Viveka Nanda Institute of Pharmaceutical Sciences, Bhuvanagiri, Nalgonda, Andhra Pradesh, India– 508001
4Holy Mary Institute of Technology and Sciences, RR District, Andhra Pradesh, India
*Corresponding Author E-mail: venkatvenki505@yahoo.in
The present work was evaluated anti-ulcer potential of the ethanol extract of leaf of Lawsonia inermis against in vivo indomethacin-induced gastric ulcer using pylorus ligation method. All the dose of the leaf extract (100, 200 and 400 mg/kg) significantly (P□0.01) reduced the ulcer index in this experiment. In conclusion, the present study provides preliminary data on the antiulcer potential of Trianthema portulacastrum leaf and support the traditional uses of the plant for the treatment of gastric ulcer.
Lawsonia inermis leaf, ethanol extract, gastric ulcer, pylorus ligation, indomethacin, induced gastric ulcers, ulcer index
