Research Journal of Pharmacy and Technology

Extraction of different parts of medicinal plants are used as a medicine, about 80% of the world population rely on plant derived medicines to cope their health care needs. Ethnobotany deals with the relationship between humans and plants in all its sophisticated issues. One of the most common problems regarding the existing gap between the traditional practice and modern medicine is scientifically unjustified use of plants in treatment for different type of infectious disease in various parts of the world including India. This experimental study was focused on the justification of botanical description, antimicrobial activity screening and determination of minimum inhibitory concentration (MIC) of plants traditionally used as a treatment of various bacterial and fungal diseases. Traditionally used medicinal plant namely Plumbago zeylanica (Plumbaginaceae), extracted by soxhlet extraction method was screened for antimicrobial activity against Escherichia coli, Staphylococcus aureus and Candida albicans, which showed better antimicrobial activity in the initial screening test, were selected for secondary screening at 100 mg/ml and 50 mg/ml.