Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2012
  • Volume: 5
  • Issue: 3

Synthesis and Fluorescence Properties of Schiff Bases of 2-chloro-3formylquinoline

  • Author:
  • B. R. Thorat, M. Mustapha, D. Khandekar, Swati Lele, P. Kamat, S. Sawant, R. Jadhav, D. Shelke, Shivaji Kolekar, R. G. Atram, R. Yamgar
  • Total Page Count: 7
  • DOI:
  • Page Number: 369 to 375

P. G. Dept of Chemistry, Govt. of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060.

Abstract

A simple and regioselective synthesis of 2-chloro-3-formylquinoline [1] by the cyclisation of N-aryacetamide has been reported by the Vilsmeier Haack reaction/cyclisation. 2-Chloro-3-formylquinoline, the formyl group shows condensation with variety of haloanilines & hydrazones and forming schiff bases N-[(E)-(2-chloroquinolin-3yl)methylidene]anilides [2a-e] which are further subjected to fluorescence study.

Keywords

Haloanilines, Formylation, Vilsmeier Haack reaction, quinoline, Schiff bases