Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2012
  • Volume: 5
  • Issue: 3

Synthesis and Fluorescence Properties of Schiff Bases of 2-chloro-3formylquinoline

  • Author:
  • B. R. Thorat, M. Mustapha, D. Khandekar, Swati Lele, P. Kamat, S. Sawant, R. Jadhav, D. Shelke, Shivaji Kolekar, R. G. Atram, R. Yamgar
  • Total Page Count: 7
  • DOI:
  • Page Number: 369 to 375

P. G. Dept of Chemistry, Govt. of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060.

Online published on 12 February, 2013.

Abstract

A simple and regioselective synthesis of 2-chloro-3-formylquinoline [1] by the cyclisation of N-aryacetamide has been reported by the Vilsmeier Haack reaction/cyclisation. 2-Chloro-3-formylquinoline, the formyl group shows condensation with variety of haloanilines & hydrazones and forming schiff bases N-[(E)-(2-chloroquinolin-3yl)methylidene]anilides [2a-e] which are further subjected to fluorescence study.

Keywords

Haloanilines, Formylation, Vilsmeier Haack reaction, quinoline, Schiff bases