Department of Pharmacy, BGC Trust University Bangladesh, Chittagong.
*Corresponding Author E-mail: saha.dibyajyoti@gmail.com
Online published on 12 February, 2013.
A study was undertaken to evaluate the effect of methanolic plant extracts of Alpinia conchigera Griff. and Plumbago indica for their antidiarrhoeal potential against castor-oil induced diarrhoea in mice. The anti-diarrheal activity was determined by evaluating the latency period and diarrhoeal frequency by counting the faeces time and number of the test groups in comparison to the control and standard loperamide groups. The methanol extracts of the A. conchigera and P. indica at the doses of 250 and 500mg/kg reduced reduced induction time of diarrhoea and total weight of the faeces in comparison to the control group and the result was statistically significant. The result obtained establishes the efficacy of these plant extracts as antidiarrhoeal agents
Antidiarrheal activity, castor oil, methanol extracts, induction time
