Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2012
  • Volume: 5
  • Issue: 8

Peptide Microarray Production on a Solid Support and its Applications

  • Author:
  • K. Pradeep, R.L. Priyadarshini, K. Vijay
  • Total Page Count: 10
  • Page Number: 1015 to 1024

University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur.

*Corresponding Author E-mail: vijai.kotra@gmail.com

Online published on 12 February, 2013.

Abstract

Peptides are polymers of amino acids linked by peptide bonds. There are various methods for the creation of peptides or peptides micro arrays. This peptides microarray, a rapidly growing tool provides both large scale and high through put capabilities for protein detection and other activities. This review is mainly focused on the production of peptide microarrays. The techniques discussed in this review are spot synthesis, photolithographic and mask less array synthesis. Peptide micro array is a versatile tool for probing of peptide-enzyme interaction, peptide –ligand interaction, etc.

Keywords

Proteomics, peptide, solid phase peptide synthesis, Chemical microarray, Peptide array, SPOT synthesis, Photolithography, Site-specific immobilization, mask less array synthesis