Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2012
  • Volume: 5
  • Issue: 8

In vitro Anti bacterial Activity of Different Solvent extracts of the Plant Calotropis procera

  • Author:
  • J. Mastanaiah1,, N.B. Prabhavathi2, T. Srivani2
  • Total Page Count: 3
  • Page Number: 1066 to 1068

1Gate School of Pharmacy, Kodad.

2St.ANN'S College of Pharmacy, Chirala.

*Corresponding Author E-mail: prabhacology@gmail.com

Online published on 12 February, 2013.

Abstract

The antibacterial activities of hexane, chloroform, methanol extracts of the plant Calotropis procera (Henna) was evaluated on bacterial strains like Escherichia coli, Klebsiella pneumonia, Lactobacillus acidophilus, Streptococcus aureus, Streptococcus mutans, Micrococcus, Streptococcus salivarius, Bacillus subtilis, Staphylococcus epidermidis, Streptococcus gordonii. The in vitro antibacterial activity of plant extracts was performed by agar cup plate/agar well diffusion method using streptomycin in dimethyl sulphoxide as a standard drug for the comparison of antibacterial activity. The results revealed that methanol extract shows lowest values of MIC when compared to other extracts. That means the highest anti bacterial activity exhibited by methanol extract. This study conclude that the methanol extract of plant Calotropis procera showed more significant activity against all tested bacterial organisms than that of the hexane and chloroform extracts.

Keywords

Calotropis procera, anti – bacterial activity, MIC, Agar well diffusion method