Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2012
  • Volume: 5
  • Issue: 8

Synthesis and Antimicrobial Evaluation of 2-(1H-1,2,3-Benzotriazol-1-yl)N-Phenylacetamide Derivatives

  • Author:
  • C. M. Jamkhandi, John Intru Disouza
  • Total Page Count: 4
  • DOI:
  • Page Number: 1072 to 1075

Department of Pharmacy, JJT University, Jhunjhunu, Rajasthan, India.

Abstract

2-(1H-1,2,3-benzotriazol-1-yl)-N-phenylacetamide derivatives find useful as anti-infective agents and substitution of bentriazole produces more potent anti-infective agents. Derivatives of benzotriazole substituted 2-(1H-1,2,3benzotriazol-1-yl)-N-phenylacetamide are synthesized and anti microbial activities have been measured against Norfloxacine and Ketoconazole as standards drugs. It is found that the derivatives from 1a to Va are shown to produce good anti microbial actions against, S. Aureus, S. Pygens, B. Subtilis, E.coli, P. Aerigenosa, C Albicanse, A Niger. The all the derivatives show satisfactory anti-microbial activities.

Keywords

Antibacterials, Anti fungals, benzotriazoles, N-phenyl acetamide derivatives