Sharad Pawar College of Pharmacy, Wanadongri, Hingna Road, Nagpur-441 110 (M.S.)
*Corresponding Author E-mail: rajbhagwat07@gmail.com
Online published on 12 February, 2013.
A simple, accurate, economical and reproducible procedure for simultaneous estimation of Prochlorperazine Maleate (PCM) and Pyridoxine Hydrochloride (PDH) in their tablet dosage form is described. The method involves absorbance of measurement at 267.5 nm (isobestic point) and 290.5 nm (λmax of Pyridoxine Hydrochloride), in 0.3 N HCl. Both drugs obey Beer-Lambert's law in concentration range of 1–5 μg/ml (PCM) and 5–25 μg/ml (PDH). The results of analysis have been validated statistically and by recovery studies.
Prochlorperazine Maleate, Pyridoxine Hydrochloride, Validation
