University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna nagar, Guntur, (A.P), India– 522510
*Corresponding Author E-mail: santosh18rox@gmail.com
Online published on 12 February, 2013.
The present study describes a simple, accurate, precise and cost effective UV-Spectrophotometric method for the estimation of Telmisartan, an anti-hypertensive drug, in bulk and pharmaceutical dosage form. The solvent used throughout the method is a combination of DMF and 0.1N HCl in the ratio 1:9. The λmax or the absorption maxima of the drug was found to be 291nm. A linear response was observed in the range of 3–15 μg/ml with a regression coefficient of 0.999. The method was then validated for different parameters. % Precision of method was find out as repeatability, day to day and analyst to analyst variation and shows the values within acceptable limit (R.S.D < 2 percentage).
Telmisartan, UV-spectrophotometry, DMF, 0.1N HCl
