Department of Pharmaceutical Chemistry, Devaki Amma Memorial College of Pharmacy, Chelembra-673634, Malappuram District, Kerala
*Corresponding Author E-mail: gbjournals@gmail.com
Online published on 31 October, 2013.
The present study was conducted to evaluate the hepatoprotective activity of ethyl acetate extract of rhizomes of Curculigo orchioides. The extract at the dose of 200 mg/kg and 400 mg/kg b. wt. was tested for its hepatoprotection, by inducing hepatotoxicity with CCl4 in Wistar albino rats and using silymarin (100 mg/kg) as the reference standard. Biochemical parameters like, SGOT, SGPT, SALP and serum bilirubin were determined to assess the hepatoprotective effect. The extract has shown significant hepatoprotection in albino rats in reducing SGOT, SGPT, SALP and serum bilirubin levels.
Antioxidant activity, hepatoprotection, Curculigo orchioides, DPPH assay, Free radical scavenging activity, Aging, Cirrhosis
