1CMR College Of Pharmacy, Hyderabad
2Department of Pharmaceutics, Vaagdevi College of Pharmacy, Warangal, Andhra Pradesh -506009
*Corresponding Author E-mail: sujithah@gmail.com
Online published on 31 October, 2013.
The fact that 40% of the newly discovered chemical entities and many existing drug molecules are poorly water soluble, presents a serious challenge to the successful formulation and marketing of new drugs in the pharmaceutical industry. This review gives a conceptual idea about Nanoemulsion (NE) system. Various formulation strategies have been reported including the use of Surfactants, Cyclodextrins, Nanoparticles, Solid dispersions, Micronization, Lipids and Permeation enhancers.Recently, much attention has been paid to lipid-based formulations with particular emphasis on Nanoemulsion and dry emulsion drug delivery systems to improve the oral bioavailability of lipophilic drugs. Nanoemulsion drug delivery systems are among the methods used to improve the oral bioavailability of poorly soluble drugs by presenting and maintaining the drug in a dissolved state, in small droplets of oil, all over its transit through the gastrointestinal tract.
Nanoemulsion, Drug delivery, Phase Diagram, Surfactant, Droplet Size