Antibacterial studies of Catharanthus roseus of Jazan province against the selected bacterial strains

The objective of this preliminary work is to identify the phyto constituents and antibacterial activity of Catharanthus roseus of Jazan province, KSA. In Saudi Arabia the plant is used for the ornamental purpose and has been found well grown in Jazan province. Active constituents from the leaves of Catharanthus roseus were isolated by cold maceration process and confirmed by respective chemical test. The anti bacterial activity of methanolic extract on various human pathogens viz Bacillus subtilis, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Klebsiella planticola and Proteus vulgaris was performed. The extracts predominately show the presence of alkaloids and flavonoids. However, there is no significant anti bacterial spectrum of activity against the tested human pathogens.