Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2013
  • Volume: 6
  • Issue: 8

Study of Antibacterial Activity of Some Plant Extracts Against Enterohemorrhagic Escherichia coli O157:H7

  • Author:
  • Mona A. El-Sayed1, Mohamed M. Kamel2, Mohamed A. El-Raei2, Samir M. Osman2, Lina Gamil1, Hisham A. Abbas1,
  • Total Page Count: 4
  • Page Number: 916 to 919

1Department of Microbiology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt

2National Research Center, Department of Water Microbiology, Cairo, Egyt

*Corresponding Author E-mail: h_abdelmonem@yahoo.com

Online published on 31 October, 2013.

Abstract

This study aimed to investigate the antibacterial activity of 14 plant extracts against Escherichia coli O157:H7. Screening of antibacterial activity was made by the agar diffusion method. Among the plants tested, twelve extracts showed strong antibacterial activity with mean inhibition zones ranging from 20.17 to 14.17 mm. The extract of Allium Kurrat showed the greatest inhibition zone. The minimum inhibitory concentration (MIC) was determined by the agar dilution method. Comparing the minimum inhibitory concentrations, the extracts of Eruca sativa and Allium Kurrat showed high activity against Escherichia coli O157:H7 with MIC values of 2.5 mg/ml. These plant extracts may provide an alternative therapeutic option for Escherichia coli O157:H7 infections.

Keywords

Enterohemorrhagic E. coli, antibacterial activity, Eruca sativa, Allium Kurrat