Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2013
  • Volume: 6
  • Issue: 9

Scopoletin (Coumarin extracted from Mengkudu): Chemical, Biological, Molecular and Pharmacokinetic insights – A Review.

  • Author:
  • U.S. Mahadeva Rao1,, Suryati Mohd Khamsah2, AB Atif1, Ahmad Zubaidi Bin A. Latif1
  • Total Page Count: 7
  • Page Number: 978 to 984

1Fakulti Perubatan dan Sains Kesihatan, Universiti Sultan Zainal Abidin

2Fakulti Pertanian dan Bioteknologi, Universiti Sultan Zainal Abidin

*Corresponding Author E-mail: raousm@gmail.com; raousm@unisza.edu.my

Online published on 31 October, 2013.

Abstract

The contemporary appraisal expanses an illumination on the extraction, screening, chemical synthesis, purity assessment, quantification, molecular and biological aspects, and pharmacokinetic studies of Scopoletin isolated from the fruit of Mengkudu (Morinda citrifolia-Rubiaceae), an edible and medicinal tropic plant. A comprehensive assortment of phytoconstituents principally alkaloids, coumarin, flavonoids, terpenoids, phenolics, vitamins, minerals, and many supplementary compounds whose activities have been proved are in existence in the Mengkudu fruit extract. This fruit has been used in traditional medicines to preclude, treat, and alleviate both communicable and noncommunicable ailments. Thus this review overlays boulevard for scopoletin extracted from fruit of Mengkudu to provide a direction for further exploration.

Keywords

Mengkudu, Noni, Rubiaceae, Scopoletin, Phytochemistry, Pharmacology, Nutraceutics