1College of Pharmacy, Jazan University, P.O. Box. 114, Jazan -45142, Kingdom of Saudi Arabia (KSA)
2Department of Pharmacognosy, Faculty of Pharmacy, Hamdard University, New Delhi, India-110062
3Department of Pharmacy, Oman Medical College, Muscat, Sultanate of Oman, Oman-130
4Departments of Pharmacology, Faculty of Pharmacy, Hamdard University, New Delhi, India-110062
5Department of Pharmacology, JJT University, Jhunjhunu, Rajasthan, India
*Corresponding Author E-mail: ali.hamdard09@gmail.com
Online published on 17 March, 2015.
Gastrointestinal complaints and pathogenic factors are the main leading causes of diarrhea. Although WHO and UNICEF are jointly working on the disease and the role of herbals and other natural products are very promising approach along with conventional methods. The present work is the evaluation of anti-diarrheal potential of traditionally used plant in Jizan province of Saudi Arabia. The lower and higher (200mg/kg bw, 400 mg/kg bw) dose of the alcoholic extracts of the plant Alkanna orientalis were used and the results were compared with the standard Loperamide drug and the higher dose 400mg/kg bw was found significant in the rat models where diarrhea was induced by castor oil administration.
Alkanna orientalis, diarrhea, castor oil, Jizan
