Department of Chemistry, Yuvaraja's College, University of Mysore, Mysore-570005, Karnataka, India
Online published on 25 June, 2015.
This review summarizes the in vitro and in vivo medicinal chemistry investigations for piperazine and morpholine analogues. Piperazine and morpholine nucleus show a broad spectrum of pharmaceutical applications, thus, in recent years scientists has developed various new methods for the synthesis of their derivatives. This review shows current tendency in the piperazine and morpholine analogues synthesis and reveals their potent pharmacophoric activities.
Piperazine, morpholine, synthesis, pharmaceutical applications
