Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2015
  • Volume: 8
  • Issue: 5

Current Trends in Ocular drug Delivery Systems and its Applications

Department of Pharmaceutics, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham University, AIMS Health Sciences Campus, Kochi, India

*Corresponding Author E-mail: anoopkr@aims.amrita.edu

Online published on 25 June, 2015.

Abstract

Ocular route of drug delivery is one of the most challenging arena faced by the pharmaceutical scientist, it is because of the complex anatomy, physiology of eye which makes the delivery of drug so complex. The challenge to the formulator is to circumvent the protective barriers of the eye without causing permanent tissue damage. Novel delivery systems have been developed for extended duration and controlled release strategy. Some of the newer, sensitive and successful ocular delivery system like inserts, biodegradable polymeric system, collagen shields, nanoparticles, phase transition systems, niosomes, liposomes, and pharmacosomes are being developed in order to attain better ocular bioavailability and sustained action of ocular drugs.

Keywords

Diffusional inserts, Osmotic inserts, Contact lenses, Soluble inserts, Bioerodible inserts