Research Journal of Pharmacy and Technology

A number of studies have shown that the hydrophobicity of solid surfaces influences adhesion of bacteria, eukaryotic cell and proteins. On the other hand bacteria and the other microbes including viral particles are evolving many different ways to use the hydrophobicity in order to adhere on to the substrates. A total of 20 clinical isolates of UPEC were subjected for antibiotic sensitivity pattern and cell surface hydrophobicity by salt aggregation method. Most of the strains showed resistant to all the antibiotics tested. 70% of isolates were showed cell surface hydrophobicity positivity. Judicial usage of antibiotics and proper detection of resistant mechanisms operating in the clinical isolates would yield better management of patient's outcome. Cell surface hydrophobicity might associate with the adhesion of UPEC in both biotic and abiotic surfaces.